These include persistent anesthesia and paresthesia. Central Nervous System (CNS) Reactions: There have been reports of adverse neurologic reactions with the use of local anesthetics.Warnings and Precautions for Bupivacaine-Containing Products The potential sensory and/or motor loss with EXPAREL is temporary and varies in degree and duration depending on the site of injection and dosage administered and may last for up to 5 days, as seen in clinical trials.EXPAREL is not recommended for the following types or routes of administration: epidural, intrathecal, regional nerve blocks other than interscalene brachial plexus nerve block, or intravascular or intra-articular use.Avoid additional use of local anesthetics within 96 hours following administration of EXPAREL.Warnings and Precautions Specific to EXPAREL Because amide-type local anesthetics, such as bupivacaine, are metabolized by the liver, EXPAREL should be used cautiously in patients with hepatic disease.EXPAREL is not recommended to be used in the following patient populations: patients Therefore, EXPAREL may be administered to the same site 20 minutes after injecting lidocaine. If EXPAREL and other non-bupivacaine local anesthetics, including lidocaine, are administered at the same site, there may be an immediate release of bupivacaine from EXPAREL.Adverse reactions with an incidence greater than or equal to 10% following EXPAREL administration via infiltration in pediatric patients six to less than 17 years of age were nausea, vomiting, constipation, hypotension, anemia, muscle twitching, vision blurred, pruritus, and tachycardia.Adverse reactions reported in adults with an incidence greater than or equal to 10% following EXPAREL administration via infiltration were nausea, constipation, and vomiting adverse reactions reported in adults with an incidence greater than or equal to 10% following EXPAREL administration via interscalene brachial plexus nerve block were nausea, pyrexia, and constipation.EXPAREL is contraindicated in obstetrical paracervical block anesthesia.Safety and efficacy have not been established in other nerve blocks.
RESOURCES & REIMBURSEMENT RESOURCES & REIMBURSEMENTĮXPAREL ® (bupivacaine liposome injectable suspension) is indicated for single-dose infiltration in patients aged 6 years and older to produce postsurgical local analgesia and in adults as an interscalene brachial plexus nerve block to produce postsurgical regional analgesia.Anesthesia: INTERSCALENE BRACHIAL PLEXUS NERVE BLOCK.Anesthesia: Interscalene brachial plexus nerve block.EXPAREL BY SPECIALTY EXPAREL BY SPECIALTY.PROPRIETARY MULTIVESICULAR LIPOSOME (pMVL) TECHNOLOGY.
0 kommentar(er)
